NASA Spaceline Current Awareness List #1,073 – 3 November 2023 (Space Life Science Research Results)

NASA Spaceline Current Awareness List #1,073 – 3 November 2023 (Space Life Science Research Results)

Astronaut Thomas Pesquet works on the Cardinal Muscle investigation within the Life Sciences Glovebox aboard the Worldwide Area Station. Credit: NASA

SPACELINE Present Consciousness Lists are distributed through listserv and can be found on the NASA Job Guide web site at Please ship any correspondence to Shawna Byrd, SPACELINE Present Consciousness Senior Editor,

Name for articles to quote within the weekly lists: Authors at NASA Facilities and NASA PIs—do you could have an article that has just lately printed or will publish within the upcoming weeks inside a peer-reviewed journal and is within the scope of house life sciences? If that’s the case, ship it our method! Ship your article to the e-mail handle talked about above. Articles obtained by Wednesday will seem inside that week’s record—articles obtained after Wednesday will seem the next week.

Papers deriving from NASA help:


Boles HO, Poulet L, Johnson CM, Torres JJ, Koss LL, Spencer LE, Massa GD.

Design, construct, and testing of {hardware} to securely harvest microgreens in microgravity.

Gravit Area Res. 2023 Oct 30;11(1):1-14.

Be aware: From the summary: “In long-duration house missions, crops will complement the astronaut weight loss plan. One proposed crop kind is microgreens, the younger seedlings of edible vegetation which might be recognized for his or her excessive dietary ranges, intense flavors, colourful look, and number of textures. Whereas these traits make microgreens promising for house crop manufacturing, their small dimension presents a singular problem inside the microgravity surroundings. To handle this problem, a microgreen planting field was developed to enhance microgreen harvest strategies each in 1 g and in microgravity with out concern for contamination by roots. Utilizing this microgreen planting field, three parabolic flights had been performed the place two totally different bagging strategies (connected and guide) and three totally different microgreen reducing strategies (Guillotine, Pepper Grinder, Scissors) had been examined.” This text could also be obtained on-line with out cost.

Journal Affect Issue: Not accessible for this journal

Funding: “The authors want to acknowledge the NASA Kennedy Area Middle for Engineering Security and Operations funds by way of their Unbiased Analysis and Expertise Growth grant, in addition to funding from the NASA Flight Alternatives program. Particularly, Earl Adams and Alexander Van Dijk from NASA Flight Alternatives had been instrumental in transferring this challenge ahead by placing the authors in touch with Dr. George Pantalos. We’re grateful to ZeroG Company for using their airplane and help in the course of the flights. The authors want to acknowledge NASA’s Area Biology Program, which funded NASA Postdoctoral Fellows CMJ and LP, and scientist GDM.”


Muanjai P, Haas C, Sies W, Mittag U, Zange J, Schönau E, Duran I, Kamandulis S, Rittweger J.

Impact of whole-body vibration frequency on muscle tensile state throughout graded plantar flexor isometric contractions.

J Exerc Sci Match. 2023 Oct 4;21(4):405-15.

Be aware: From the summary: “Acute physiological and biomechanical alterations have been reported following whole-body vibration (WBV). Stiffening of muscular tissues has solely been anecdotally reported in response to WBV. Accordingly, this research investigated lively plantar flexor muscle stiffness in response to a single WBV bout at 4 mechanical vibration frequencies.”

Journal Affect Issue: 2.8

Funding: “This analysis was funded by grants from German Aerospace Middle (DLR), the Burapha College Analysis and Growth Fund and Erasmus program from Lithuanian Sports activities College. CH’s involvement on this analysis was supported by the Translational Analysis Institute for Area Well being by way of Cooperative Settlement NNX16AO69A and by the College of Texas Medical Department and the NASA Graduate Medical Training Coaching in Aerospace Drugs Cooperative Settlement NNX07A134A.”


Niclou A, Sarma MS.

The now and way forward for human biology on the extremes: An introduction to the particular problem.

Am J Hum Biol. 2023 Oct 26;e24006.

PI: M.S. Sarma

Journal Affect Issue: 2.9

Funding: “AN is supported by the Nationwide Institute of Diabetes and Digestive and Kidney Ailments of the Nationwide Institutes of Well being beneath Award Quantity T32DK064584. MSS is supported by the Translational Institute for Area Well being by way of the Nationwide Aeronautics and Area Administration Cooperative Settlement NNX16AO69A and the Nationwide Institute on Deafness and Different Communication Issues of the Nationwide Institute of Well being beneath Award Quantity 5T32DC000023‐33.”


Vimal VP, Panic AS, Lackner JR, DiZio P.

Vibrotactile suggestions as a countermeasure for spatial disorientation.

Entrance Physiol. 2023 Nov 3;14:1249962.

PI: V.P. Vimal

Be aware: From the summary: “Spaceflight could make astronauts vulnerable to spatial disorientation which is among the main causes of deadly plane accidents. In our experiment, blindfolded contributors used a joystick to stability themselves whereas inside a multi-axis rotation machine (MARS) in both the vertical or horizontal roll aircraft.” This text could also be obtained on-line with out cost.

Journal Affect Issue: 4.0

Funding: “VV was supported by NASA’s Human Analysis Program beneath grant 80NSSC22K0758. JL and PD had been supported by NAMRU N0018923P0725.”


Different papers of curiosity:


Cucinotta FA, Pak S.

Most cancers and circulatory illness dangers for the biggest photo voltaic particle occasions within the house age.

Life Sci Area Res. 2023 Oct 31. On-line forward of print.

Be aware: From the summary: “On this paper we use the NASA Area Most cancers Threat (NSCR model 2022) mannequin to foretell most cancers and circulatory illness dangers utilizing power spectra representing the biggest SPE’s [solar particle events] noticed within the house age.”


Dobney W, Mols L, Mistry D, Tabury Okay, Baselet B, Baatout S.

Analysis of deep house exploration dangers and mitigations towards radiation and microgravity.

Entrance Nucl Med. 2023 Sep 21;3:1225034. Evaluation.

Be aware: This text is a part of Analysis Matter “Insights in Dosimetry and Radiation Security” ( and could also be obtained on-line with out cost.


Li Y, Guo J, Khaksarighiri S, Dobynde MI, Zhang J, Liu B, Wimmer-Schweingruber RF.

The impression of house radiation on brains of future Martian and lunar explorers.

Area Climate. 2023 Oct 3;21(10):e2023SW003470.

Be aware: From the summary: “Astronauts will likely be going through many dangers when they’re away from Earth’s surroundings, amongst which radiation is among the most significant and troublesome points. Area radiation publicity from energetic particles of Photo voltaic Energetic Particles (SEPs) and Galactic Cosmic Rays (GCRs) can adversely impression the Central Nervous System (CNS) by inducing acute (i.e., mission essential) and persistent (i.e., post-mission) results, respectively.” This text could also be obtained on-line with out cost.


Wang S, Wang T, Zeng X, Chu XY, Zhuoma D, Zhao Y, Chen YZ.

Exploring outer house biophysical phenomena through SpaceLID.

Sci Rep. 2023 Oct 13;13(1):17400.

Be aware: From the summary: “Intensive investigations in outer house have revealed not solely how life adapts to the house surroundings, but in addition that attention-grabbing biophysical phenomena happen. These phenomena have an effect on human well being and different life types (animals, vegetation, micro organism, and fungi), and to make sure the protection of future human house exploration should be additional investigated. This requires joint analysis efforts between biologists and physicists, as these phenomena current cross-disciplinary obstacles.”


Alani F, Iranbakhsh A, Ebadi M, Hassanpour H, Hekmat A.

Simulated microgravity improved secondary metabolism in Physalis alkekengi through influencing gene expression and DNA methylation in a lightweight quality-dependent method.

Acta Physiol Plant. 2023 Oct 3;45(11):129.


Cui J, Yi Z, Chen D, Fu Y, Liu H.

Microgravity stress alters bacterial group meeting and co-occurrence networks throughout wheat seed germination.

Sci Whole Environ. 2023 Sep 10;890:164147.


Doré J, Ortega Ugalde S.

Human-microbes symbiosis in well being and illness, on Earth and past planetary boundaries.

Entrance Astron Area Sci. 2023 Sep 22;10:1180522.

Be aware: This text is a part of Analysis Matter “Shows on the 2022 MELiSSA Convention – Present and Future Methods to Closed Life Help Methods” (—current-and-future-ways-to-closed-life-support-systems#overview) and could also be obtained on-line with out cost.


Zhang H, Liu X, Wu R, Li Y.

[Gut microbial dysbiosis under space environment: A review.]

Sheng Wu Gong Cheng Xue Bao. 2023 Oct 25;39(10):4075-84. Evaluation. Chinese language.

Be aware: This text could also be obtained on-line with out cost.


Feng J, Wu B, Cao Z, Chen H, Lan T, Qin H, Shi Y, Huang W, Li Y.

Results of thirty days isolation on consideration networks: A behavioral and event-related potential research.

Neurosci Bull. 2023 Oct 27. On-line forward of print.


James AB, Sharples C, Laird J, Armstrong EM, Guo W, Tzioutziou N, Zhang R, Brown JWS, Nimmo HG, Jones MA.

REVEILLE2 thermosensitive splicing: A molecular foundation for the mixing of nocturnal temperature data by the Arabidopsis circadian clock.

New Phytol. 2023 Oct 28. On-line forward of print.


Bailey S, Fraser Okay.

Advancing our understanding of the affect of drug induced modifications within the intestine microbiome on bone well being.

Entrance Endocrinol (Lausanne). 2023 Oct 9;14:1229796. Evaluation.

Be aware: This text is a part of Analysis Matter “The Position of the Intestine Microbiota on Bone Mass in Well being and Illness” ( and could also be obtained on-line with out cost.


Yeo H-S, Lim J-Y.

Results of train prehabilitation on muscle atrophy and contractile properties in hindlimb-unloaded rats.

Muscle & Nerve. 2023 Sep 29. On-line forward of print.

Be aware: Hindlimb unloading research.


Li Y, Solar W, Li J, Du R, Xing W, Yuan X, Zhong G, Zhao D, Liu Z, Jin X, Pan J, Li Y, Li Q, Kan G, Han X, Ling S, Solar X, Li Y.

HuR-mediated nucleocytoplasmic translocation of HOTAIR relieves its inhibition of osteogenic differentiation and promotes bone formation.

Bone Res. 2023 Oct 23;11:53.

Be aware: This text could also be obtained on-line with out cost.


Noguchi M, Ihara T, Suzuki Okay, Yokoya A.

Temporal dynamic regulation of autophagy and senescence induction in response to radiation publicity.

Radiat Res. 2023 Oct 30. On-line forward of print.


Tomasino AM, Olson JD, Schaaf GW, Cox AO, Furdui CM, Cline JM, Cohen EP.

A brand new methodology for estimating glomerular filtration fee in rhesus macaques (Macaca mulatta).

Radiat Res. 2023 Oct 30. On-line forward of print.


Zhao Z-A, Zhang N-N, Cui Y, Chen H-S.

The impact of head-down tilt in experimental acute ischemic stroke.

Eur Neurol. 2023 Oct 18;30(1):155-61.

Be aware: Head-down tilt research.


Tang J, Weiss H, Stirling L.

A comparability of sensorimotor evaluation accuracy between augmented actuality and touchscreen environments.

Proc Hum Components Ergon Soc Annu Meet. 2023 Oct 20;21695067231192547.


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